Accidents happen—whether it’s a child wetting the bed, a pet mishap, or an unexpected spill. If you're wondering how to wash a mattress with urine, you’re not alone. While it may seem like a disaster, urine stains and smells can be removed effectively if treated properly and promptly. This guide walks you through what to do step-by-step to restore your mattress to a clean and odor-free condition.

Understand the Type of Urine Stain First
Before jumping into cleaning, it's important to identify whether the urine is:
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Fresh (still wet)
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Old or dried
The method you use to wash the mattress depends on how long the urine has been there. Fresh stains are easier to treat, while dried ones require deeper cleaning.
What You’ll Need to Clean Urine from a Mattress
Gather the following supplies:
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Paper towels or clean absorbent cloths
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White vinegar
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Spray bottle
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Enzyme cleaner (for older stains or pet urine)
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Vacuum with brush attachment
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Optional: Hydrogen peroxide (spot-testing required)
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Waterproof mattress protector (for future prevention)
How to Wash a Mattress with Urine (Fresh Stain)
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Blot the Urine Immediately
Use paper towels or a clean cloth to blot as much liquid as possible. Do not rub—it spreads the stain. -
Spray Vinegar Solution
Mix equal parts white vinegar and water in a spray bottle. Spray the affected area generously to neutralize odor and bacteria. -
Let It Sit
Allow the solution to soak in for about 10–15 minutes to break down the urine compounds. -
Blot Again
Dab the area to remove excess liquid. -
Apply Baking Soda
Sprinkle a generous layer of baking soda over the damp area. This will absorb moisture and eliminate odor. -
Wait 6–8 Hours (or Overnight)
Let the baking soda work its magic. If possible, leave it overnight. -
Vacuum Thoroughly
Use a vacuum to remove all baking soda residue. If the stain or smell remains, repeat the process.
How to Remove Dried Urine Stains from a Mattress
Dried urine can cause lingering odors and discoloration. Here’s how to treat it:
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Spray the stain with an enzyme-based cleaner, specifically designed to break down urine proteins.
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Let it sit for at least 15 minutes, or follow the product instructions.
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Blot the area dry.
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Apply baking soda, wait several hours, then vacuum.
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For stubborn discoloration, carefully apply a small amount of hydrogen peroxide (spot-test first).
How to Remove Urine Smell from a Mattress
Even after the stain is gone, the smell might linger. Here's what to do:
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Use baking soda liberally—it absorbs odor molecules.
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Air out the mattress in direct sunlight if possible.
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Try a fabric-safe deodorizing spray for extra freshness.
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Use activated charcoal or odor-absorbing bags in the room for ongoing control.
Can You Wash a Mattress in a Washing Machine?
No—mattresses cannot be machine washed. Doing so may damage the foam and structure, and encourage mold growth. Always stick to surface cleaning methods and ensure the mattress dries completely.
Protecting Your Mattress from Future Urine Accidents
The best way to avoid repeating this process is to use a waterproof mattress protector. Look for one that is:
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Machine-washable
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Breathable and noiseless
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Fitted tightly to prevent leaks
Ideal for children’s beds, pet households, elderly care, or anyone prone to night accidents.
When to Replace Your Mattress
Even with deep cleaning, sometimes the damage is too extensive:
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Persistent urine odor that doesn’t go away
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Visible mold or mildew
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Structural damage (foam sagging, disintegration)
In such cases, consider replacing your mattress with a hypoallergenic and washable option.

Final Thoughts: Act Fast and Clean Smart
Knowing how to wash a mattress with urine can save you from long-term odor, bacteria buildup, and discomfort. The key is acting fast, using the right supplies, and drying the mattress thoroughly.
Don’t forget to protect your investment going forward with a quality mattress cover—because accidents might be unavoidable, but damage is not.